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Am J Obstet Gynecol. 2011 Oct;205(4):374.e1-9. doi: 10.1016/j.ajog.2011.07.015. Epub 2011 Jul 20.

A systematic review of severe morbidity in infants born late preterm.

Author information

1
Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands. m.j.teune@amc.uva.nl

Abstract

OBJECTIVE:

Late-preterm infants (34 weeks 0/7 days-36 weeks 6/7 days' gestation) represent the largest proportion of singleton preterm births. A systematic review was performed to access the short- and/or long-term morbidity of late-preterm infants.

STUDY DESIGN:

An electronic search was conducted for cohort studies published from January 2000 through July 2010.

RESULTS:

We identified 22 studies studying 29,375,675 infants. Compared with infants born at term, infants born late preterm were more likely to suffer poorer short-term outcomes such as respiratory distress syndrome (relative risk [RR], 17.3), intraventricular hemorrhage (RR, 4.9), and death <28 days (RR, 5.9). Beyond the neonatal period, late-preterm infants were more likely to die in the first year (RR, 3.7) and to suffer from cerebral palsy (RR, 3.1).

CONCLUSION:

Although the absolute incidence of neonatal mortality and morbidity in infants born late preterm is low, its incidence is significantly increased as compared with infants born at term.

PMID:
21864824
DOI:
10.1016/j.ajog.2011.07.015
[Indexed for MEDLINE]

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