Abstract
Objective:
Pancreatic neuroendocrine tumors expressing serotonin (carcinoid tumors) account for a small portion of pancreatic neuroendocrine tumors. The purpose of this study was to describe cases of small serotonin-producing pancreatic neuroendocrine tumors associated with pancreatic duct obstruction.
Conclusion:
Serotonin produced by pancreatic neuroendocrine tumors can induce fibrosis and pancreatic duct obstruction. Pancreatic neuroendocrine tumors should be considered when CT shows a small hypervascular mass associated with upstream pancreatic duct dilatation or atrophy. Evidence of small pancreatic neuroendocrine tumors should be sought in cases of idiopathic pancreatic duct stenosis.
MeSH terms
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Adult
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Carcinoid Tumor / diagnostic imaging*
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Carcinoid Tumor / metabolism
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Carcinoid Tumor / pathology
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Constriction, Pathologic / diagnostic imaging
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Constriction, Pathologic / etiology
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Constriction, Pathologic / pathology
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Female
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Humans
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Incidental Findings
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Male
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Middle Aged
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Neuroendocrine Tumors / diagnostic imaging*
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Neuroendocrine Tumors / metabolism
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Neuroendocrine Tumors / pathology
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Pancreatic Diseases / diagnostic imaging
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Pancreatic Diseases / pathology*
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Pancreatic Ducts / diagnostic imaging
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Pancreatic Ducts / pathology*
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Pancreatic Neoplasms / diagnostic imaging*
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Pancreatic Neoplasms / metabolism
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Pancreatic Neoplasms / pathology
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Serotonin / metabolism
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Tomography, X-Ray Computed*
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Ultrasonography, Interventional