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Zh Vyssh Nerv Deiat Im I P Pavlova. 2011 May-Jun;61(3):322-31.

[Sleep deprivation effect upon spatial memory consolidation in rats after one-day learning in a Morris water maze].

[Article in Russian]


The effect of sleep deprivation by 'carousel' method on spatial memory consolidation in a Morris water maze was studied in Wistar male rats after one-day learning (in accordance to a protocol by Frick et al., 2000). It was found that after fast 3-hr learning the memory trace retains during 24-hr. Twenty four hour sleep deprivation followed learning impaired consolidation of spatial memory. So the rat model of a one-day learning is suitable for the studying of neurophysiological mechanisms of sleep deprivation effects on spatial memory consolidation.

[Indexed for MEDLINE]

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