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Fitoterapia. 2011 Dec;82(8):1198-201. doi: 10.1016/j.fitote.2011.08.001. Epub 2011 Aug 11.

Neuroprotective cadinane sesquiterpenes from the resinous exudates of Commiphora myrrha.

Author information

1
College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, China.

Abstract

Three new cadinane sesquiterpenes, commiterpenes A-C, were isolated from the resinous exudates of Commiphora myrrha. Their structures and relative configurations were elucidated by spectroscopic methods (IR, ESIMS, HRESIMS, 1D and 2D NMR). All the isolated sesquiterpenes showed neuroprotective effects against MPP+-induced neuronal cell death in SH-SY5Y cells.

PMID:
21856385
DOI:
10.1016/j.fitote.2011.08.001
[Indexed for MEDLINE]

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