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Cardiovasc Revasc Med. 2012 Jan-Feb;13(1):66-8. doi: 10.1016/j.carrev.2011.06.005.

Takotsubo cardiomyopathy: reversible elevation in microcirculatory resistance.

Author information

1
Department of Cardiology, St Vincent's Hospital, Melbourne, Victoria, Australia. jamielayland@hotmail.com

Abstract

We present a case of takotsubo cardiomyopathy and demonstrate an initial elevation of microcirculatory resistance (IMR) that reduced on follow-up evaluation. This corresponded with improvements in left ventricular function. We postulate that the changes in microvascular resistance reflect favourable left ventricular microvascular remodelling. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition.

PMID:
21856251
DOI:
10.1016/j.carrev.2011.06.005
[Indexed for MEDLINE]

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