Send to

Choose Destination
Clin Microbiol Infect. 2011 Oct;17(10):1520-4. doi: 10.1111/j.1469-0691.2011.03600.x. Epub 2011 Aug 18.

Clonal dissemination of Klebsiella pneumoniae ST258 harbouring KPC-2 in Argentina.

Author information

Servicio Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS Dr Carlos G. Malbrán, Ciudad Autónoma de Buenos Aires, Argentina.


The present work describes the abrupt emergence of Klebsiella pneumoniae carbapenemase (KPC) and characterizes the first 79 KPC-producing enterobacteria from Argentina (isolated from 2006 to 2010). The emergence of bla(KPC-2) was characterized by two patterns of dispersion: the first was the sporadic occurrence in diverse enterobacteria from distant geographical regions, harbouring plasmids of different incompatibility groups and bla(KPC-2) in an unusual genetic environment flanked by ISKpn8-Δbla(TEM-1) and ISKpn6-like. bla(KPC-2) was associated with IncL/M transferable plasmids; the second was the abrupt clonal spread of K. pneumoniae ST258 harbouring bla(KPC-2) in Tn4401a.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center