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Int J Med Sci. 2011;8(6):461-6. Epub 2011 Aug 2.

Patient specification quality assurance for glioblastoma multiforme brain tumors treated with intensity modulated radiation therapy.

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1
King Faisal Specialist Hospital & Research Centre, Dept. of Biomedical Physics, Riyadh 11211, Saudi Arabia.

Abstract

The aim of this study was to evaluate the significance of performing patient specification quality assurance for patients diagnosed with glioblastoma multiforme treated with intensity modulated radiation therapy. The study evaluated ten intensity modulated radiation therapy treatment plans using 10 MV beams, a total dose of 60 Gy (2 Gy/fraction, five fractions a week for a total of six weeks treatment). For the quality assurance protocol we used a two-dimensional ionization-chamber array (2D-ARRAY). The results showed a very good agreement between the measured dose and the pretreatment planned dose. All the plans passed >95% gamma criterion with pixels within 5% dose difference and 3 mm distance to agreement. We concluded that using the 2D-ARRAY ion chamber for intensity modulated radiation therapy is an important step for intensity modulated radiation therapy treatment plans, and this study has shown that our treatment planning for intensity modulated radiation therapy is accurately done.

KEYWORDS:

Photon-beam dose calculation; dose verification; gamma index; glioblastoma multiforme.; intensity modulated radiation therapy; quality assurance

PMID:
21850196
PMCID:
PMC3156993
[Indexed for MEDLINE]
Free PMC Article
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