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Nat Rev Cancer. 2011 Aug 18;11(9):657-70. doi: 10.1038/nrc3092.

What does physics have to do with cancer?

Author information

1
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA. michor@jimmy. harvard.edu

Abstract

Large-scale cancer genomics, proteomics and RNA-sequencing efforts are currently mapping in fine detail the genetic and biochemical alterations that occur in cancer. However, it is becoming clear that it is difficult to integrate and interpret these data and to translate them into treatments. This difficulty is compounded by the recognition that cancer cells evolve, and that initiation, progression and metastasis are influenced by a wide variety of factors. To help tackle this challenge, the US National Cancer Institute Physical Sciences-Oncology Centers initiative is bringing together physicists, cancer biologists, chemists, mathematicians and engineers. How are we beginning to address cancer from the perspective of the physical sciences?

PMID:
21850037
PMCID:
PMC3711102
DOI:
10.1038/nrc3092
[Indexed for MEDLINE]
Free PMC Article

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