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Cancer Invest. 2011 Oct;29(8):557-63. doi: 10.3109/07357907.2011.606250. Epub 2011 Aug 15.

Two-year clinical experience with tomotherapy: the French national cancer institute project on implementing new technology.

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Department of Radiation Oncology, Hôpital Européen Georges Pompidou, Paris Descartes University, Sorbonne Cité Paris, France.


The pooled 2-year clinical experience using three tomotherapy units installed in France in 2007 is presented. Treatment indications and protocols were devised for each disease site and were the result of a consensus. A total of 642 patients were treated for central nervous system, head and neck, thoracic, abdominal, and pelvic tumors. Overall, grade 3, 4, and 5 acute toxicity was 10.7%, 0.3%, and 0.2%, respectively. Grade 3 chronic toxicity was 1.2%. There was no grade 4 or 5 chronic toxicity. The use of tomotherapy in a broad clinical practice is safe, and acute and chronic toxicity both are acceptable for all anatomical locations.

[Indexed for MEDLINE]

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