[The study of polymorphism rs9939609 FTO gene in patients with overweight and obesity]

Vopr Pitan. 2011;80(3):13-7.
[Article in Russian]

Abstract

In 94 persons living in the Moscow region, with a body mass index >25 kg/m2 were identified on the polymorphism rs9939609 FTO gene. The results showed that 83% of them were carriers of the mutant allele, and 43%--contained the mutant allele in the homozygous state. Carriers of the mutant allele rs9939609 FTO gene were distinguished by higher absolute and relative values of fat mass and triglycerides in serum.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Alleles*
  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • Body Mass Index
  • Female
  • Heterozygote
  • Homozygote
  • Humans
  • Male
  • Middle Aged
  • Mutation*
  • Obesity / blood
  • Obesity / genetics*
  • Polymorphism, Genetic*
  • Proteins / genetics*
  • Triglycerides / blood

Substances

  • Proteins
  • Triglycerides
  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • FTO protein, human