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Bioinformatics. 2011 Oct 15;27(20):2903-4. doi: 10.1093/bioinformatics/btr467. Epub 2011 Aug 11.

ChimeraScan: a tool for identifying chimeric transcription in sequencing data.

Author information

1
Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Abstract

SUMMARY:

Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.

AVAILABILITY:

http://chimerascan.googlecode.com

CONTACT:

cmaher@dom.wustl.edu

SUPPLEMENTARY INFORMATION:

Supplementary data are available at Bioinformatics online.

PMID:
21840877
PMCID:
PMC3187648
DOI:
10.1093/bioinformatics/btr467
[Indexed for MEDLINE]
Free PMC Article

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