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Curr Opin Clin Nutr Metab Care. 2011 Sep;14(5):440-4. doi: 10.1097/MCO.0b013e328348ed85.

Assessing vitamin D status.

Author information

1
Creighton University, Omaha, Nebraska 68131, USA. rheaney@creighton.edu

Abstract

PURPOSE OF REVIEW:

To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status.

RECENT FINDINGS:

Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D status to health and disease.

CONCLUSION:

The distinction between deficiency and insufficiency is not useful or necessary. Serum 25(OH)D values below 120  nmol/l (48  ng/ml) are associated with preventable disease and are therefore indicative of deficiency. The upper limit of the normal range can be set at 225  nmol/l (90  ng/ml), although toxicity is rare below 500  nmol/l (200  ng/ml).

PMID:
21832900
DOI:
10.1097/MCO.0b013e328348ed85
[Indexed for MEDLINE]

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