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J Clin Microbiol. 2011 Oct;49(10):3644-6. doi: 10.1128/JCM.05035-11. Epub 2011 Aug 10.

Comparison of multilocus variable-number tandem-repeat analysis and multilocus sequence typing for differentiation of hemolytic-uremic syndrome-associated Escherichia coli (HUSEC) collection strains.

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1
Institute of Hygiene and National Consulting Laboratory for Hemolytic Uremic Syndrome, University Hospital Münster, Robert-Koch-Strasse 41, 48149 Münster, Germany.

Abstract

Multilocus variable-number tandem-repeat analysis (MLVA) was compared to multilocus sequence typing (MLST) to differentiate hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli strains. Although MLVA--like MLST--was highly discriminatory (index of diversity, 0.988 versus 0.984), a low level of concordance demonstrated the limited ability of MLVA to reflect long-term evolutionary events.

PMID:
21832012
PMCID:
PMC3187322
DOI:
10.1128/JCM.05035-11
[Indexed for MEDLINE]
Free PMC Article
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