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Org Lett. 2011 Sep 2;13(17):4510-3. doi: 10.1021/ol201652r. Epub 2011 Aug 9.

A new half-condensed Schiff base compound: highly selective and sensitive pH-responsive fluorescent sensor.

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1
Department of Chemistry, Burdwan University, Golapbag, West Bengal, India.

Abstract

A new probe, 3-[(3-benzyloxypyridin-2-ylimino)methyl]-2-hydroxy-5-methylbenzaldehyde (1-H) behaves as a highly selective fluorescent pH sensor in a Britton-Robinson buffer at 25 °C. The pH titrations show a 250-fold increase in fluorescence intensity within the pH range of 4.2 to 8.3 with a pK(a) value of 6.63 which is valuable for studying many of the biological organelles.

PMID:
21827136
DOI:
10.1021/ol201652r
[Indexed for MEDLINE]
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