Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Neurosci. 2011 Aug 7;14(9):1109-11. doi: 10.1038/nn.2895.

Harmonin inhibits presynaptic Cav1.3 Ca²⁺ channels in mouse inner hair cells.

Author information

1
Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa, USA.

Abstract

Harmonin is a scaffolding protein that is required for normal mechanosensory function in hair cells. We found a presynaptic association of harmonin and Ca(v)1.3 Ca(2+) channels at the mouse inner hair cell synapse, which limits channel availability through a ubiquitin-dependent pathway.

PMID:
21822269
PMCID:
PMC3164920
DOI:
10.1038/nn.2895
[Indexed for MEDLINE]
Free PMC Article

Publication types, MeSH terms, Substances, Grant support

Publication types

MeSH terms

Substances

Grant support

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Support Center