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Skin Pharmacol Physiol. 2012;25(1):2-8. doi: 10.1159/000330521. Epub 2011 Aug 5.

An encapsulated fruit and vegetable juice concentrate increases skin microcirculation in healthy women.

Author information

1
Institute of Biochemistry and Molecular Biology I, Heinrich Heine University, Düsseldorf, Germany.

Abstract

BACKGROUND/AIM:

Microcirculation in the dermis of the skin is important for nutrient delivery to this tissue. In this study, the effects of a micronutrient concentrate (Juice Plus+®; 'active group'), composed primarily of fruit and vegetable juice powder, on skin microcirculation and structure were compared to placebo.

STUDY DESIGN/METHODS:

This 12-week study had a monocentric, double-blind placebo and randomized controlled design with two treatment groups consisting of 26 healthy middle-aged women each. The 'oxygen to see' device was used to evaluate microcirculation. Skin density and thickness were measured using ultrasound. Measurements for skin hydration (Corneometer®), transepidermal water loss and serum analysis for carotenoids and α-tocopherol were also performed.

RESULTS:

By 12 weeks, microcirculation of the superficial plexus increased by 39%. Furthermore, skin hydration increased by 9% while skin thickness increased by 6% and skin density by 16% in the active group. In the placebo group, microcirculation decreased, and a slight increase in skin density was observed.

CONCLUSION:

Ingestion of a fruit- and vegetable-based concentrate increases microcirculation of the skin at 12 weeks of intervention and positively affects skin hydration, density and thickness.

PMID:
21822034
DOI:
10.1159/000330521
[Indexed for MEDLINE]
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