Send to

Choose Destination
See comment in PubMed Commons below
Vet J. 2012 Jun;192(3):494-7. doi: 10.1016/j.tvjl.2011.06.040. Epub 2011 Aug 4.

Serum butyrylcholinesterase activity in dogs with diabetes mellitus.

Author information

Department of Animal Medicine and Surgery, Veterinary School, University of Murcia, 30100 Murcia, Spain.


Increased serum butyrylcholinesterase (BChE) activity is a feature of diabetes mellitus (DM) in humans and rats. The objective of this study was to evaluate serum BChE activity in diabetic dogs. The activity of the enzyme was assessed in three cohorts of animals: (1) dogs with naturally occurring DM (n=74); (2) clinically normal dogs (n=74); and (3) dogs with various other diseases (n=74). A statistically significant increase in BChE activity was found in the diabetic dogs (7.59 ± 2.9 kUI/L) compared with the clinically normal animals (6.12 ± 1.94 kUI/L; P<0.05), and with the dogs with other diseases (5.55 ± 2.06 kUI/L; P<0.01). Such increased activity could be the result of the altered glucose and lipid metabolism that occurs in DM.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center