Send to

Choose Destination
Dis Esophagus. 2012 Feb;25(2):159-65. doi: 10.1111/j.1442-2050.2011.01228.x. Epub 2011 Aug 5.

Can the rat be used as a valid model of human esophageal adenocarcinoma?

Author information

Department of Upper GI Surgery, Norfolk and Norwich University Hospital, Norwich, UK.


Animal models of Barrett's metaplasia and esophageal adenocarcinoma are important to further characterize the disease and test potential therapies. This paper reviews the development of the surgical model of esophageal adenocarcinoma in the rat and considers whether this model provides a biologically accurate representation of Barrett's esophagus and esophageal adenocarcinoma in humans.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center