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J Addict Med. 2011 Dec;5(4):300-1. doi: 10.1097/ADM.0b013e318221fbfa.

A coincidence of addiction to "Kratom" and severe primary hypothyroidism.

Author information

1
Cleveland Clinic Alcohol and Drug Recovery Center, Cleveland, OH, USA. ssheleg@yahoo.com

Abstract

Here we present a case of a coincidence of addiction to "Kratom" (botanically known as Mitragyna speciosa Korth) and developed severe primary hypothyroidism. We are discussing a possibility that high dose of indole alkaloid mitragynine (the major alkaloid identified from "Kratom") might reduce the normal response of the thyroid gland to thyroid-stimulating hormone resulting in primary hypothyroidism. Further experimental investigations of mitragynine as a possible suppressor of thyroid gland function would be a matter of interest.

PMID:
21817918
DOI:
10.1097/ADM.0b013e318221fbfa
[Indexed for MEDLINE]

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