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Antivir Ther. 2011;16(5):621-8. doi: 10.3851/IMP1813.

Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding.

Author information

1
Infectious Diseases Unit, Alfred Hospital, Melbourne, Australia. m.giles@alfred.org.au

Abstract

It is estimated there are 350-400 million people worldwide chronically infected with HBV. Many of these are women and of reproductive age. As such, they may face therapeutic decisions regarding antiviral therapy and the implication this may have on future or current pregnancies. This article reviews the data of all antivirals licensed for use against hepatitis B infection regarding teratogenicity, carcinogenicity, clinical experience during pregnancy, placental transfer and excretion in breast milk.

PMID:
21817183
DOI:
10.3851/IMP1813
[Indexed for MEDLINE]

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