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Clin Lymphoma Myeloma Leuk. 2011 Aug;11(4):336-41. doi: 10.1016/j.clml.2011.02.002. Epub 2011 May 6.

A retrospective study to evaluate the work-up and follow-up of patients with monoclonal gammopathy of undetermined significance.

Author information

1
Institute for Myeloma and Bone Cancer Research, West Hollywood, CA 90069, USA. jberenson@imbcr.org

Abstract

BACKGROUND:

Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell proliferative disorder that transforms into multiple myeloma and other serious B-cell disorders at an approximate rate of 1% per year; these patients are also at increased risk for fractures.

PATIENTS AND METHODS:

We conducted a retrospective, multicenter study of 100 patients from seven community health clinics to gain a better understanding of the work-up, follow-up, and treatment of these patients.

RESULTS:

MGUS patients appear to undergo inadequate work-up, follow-up, and treatment in the community setting.

CONCLUSIONS:

Physicians should adhere to recently established guidelines to ensure that MGUS patients receive optimal care for this condition.

PMID:
21816371
DOI:
10.1016/j.clml.2011.02.002
[Indexed for MEDLINE]
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