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Cell Stem Cell. 2011 Aug 5;9(2):89-91. doi: 10.1016/j.stem.2011.07.009.

A simple code for installing hepatocyte function.

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  • 1Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA.

Abstract

Forced lineage conversion of accessible cell types can supply scarce or inaccessible cells for research and therapy. Two papers in Nature now report the identification of transcription factors sufficient for inducing therapeutically effective hepatocyte function in fibroblasts (Huang et al., 2011; Sekiya and Suzuki, 2011).

PMID:
21816357
DOI:
10.1016/j.stem.2011.07.009
[PubMed]
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