Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Prod Commun. 2011 Jun;6(6):813-8.

Identification by LC-ESI-MS of flavonoids responsible for the antioxidant properties of Mallotus species from Vietnam.

Author information

1
Institute of Natural Products Chemistry, Hoang Quoc Viet Road, Nghia Do Cau Giay, 18, Vietnam Academy of Science and Technology, Hanoi, Vietnam.

Abstract

Several Mallotus species (Euphorbiaceae) are used in Vietnam as edible plants or as traditional medicines for different indications, some related to the treatment of inflammatory diseases. This study investigated the antioxidant activities of 33 samples from 17 Vietnamese Mallotus species. We also evaluated potential cytotoxic activity against human cervix carcinoma HeLa and human lung fibroblast WI-38 cells. Our aim is to develop safe dietary supplements with a protective effect against various diseases caused by tissue damage and the acceleration of the aging process linked to reactive oxygen species. These tests allowed the identification of non-cytotoxic plant species exhibiting significant antiradical properties. These antioxidant properties may be explained by their polyphenol composition. The antioxidant activity of the most active Mallotus species was further analyzed with and without tannins removal. We also identified by LC-ESI-MS some flavonoids responsible for a part of this activity.

PMID:
21815417
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center