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Arch Microbiol. 2011 Oct;193(10):693-9. doi: 10.1007/s00203-011-0739-0. Epub 2011 Aug 4.

Genomics of iron acquisition in the plant pathogen Erwinia amylovora: insights in the biosynthetic pathway of the siderophore desferrioxamine E.

Author information

1
Plant Protection Division, Agroscope Changins-W├Ądenswil ACW, 8820, W├Ądenswil, Switzerland. theo.smits@acw.admin.ch

Abstract

Genomics has clarified the biosynthetic pathway for desferrioxamine E critical for iron acquisition in the enterobacterial fire blight pathogen Erwinia amylovora. Evidence for each of the individual steps and the role of desferrioxamine E biosynthesis in pathogen virulence and cell protection from host defenses is presented. Using comparative genomics, it can be concluded that desferrioxamine biosynthesis is ancestral within the genera Erwinia and Pantoea.

PMID:
21814817
DOI:
10.1007/s00203-011-0739-0
[Indexed for MEDLINE]

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