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Clin Infect Dis. 2011 Aug;53(4):369-72. doi: 10.1093/cid/cir406.

Treatment outcomes of isoniazid-resistant tuberculosis patients, Western Cape Province, South Africa.

Author information

1
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. krjacobson@partners.org

Abstract

We report treatment outcomes from a retrospective cohort of patients with isoniazid-monoresistant tuberculosis in rural South Africa. Sixteen percent of patients had poor outcomes, 61% of whom progressed to multidrug-resistant tuberculosis. These data reveal the need for early identification and aggressive follow-up of isoniazid monoresistance to increase treatment success.

PMID:
21810750
PMCID:
PMC3202325
DOI:
10.1093/cid/cir406
[Indexed for MEDLINE]
Free PMC Article

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