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Ann Indian Acad Neurol. 2011 Apr;14(2):120-1. doi: 10.4103/0972-2327.82801.

Subacute sclerosing panencephalitis presenting as mania.

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Department of Psychiatry, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Expression of concern in


Subacute sclerosing panencephalitis (SSPE) is a rare, invariably fatal degenerative disease of the central nervous system developing after measles infection. Besides neurological symptoms as initial presenting symptoms, rare reports of its presentation with pure psychiatric symptoms have been reported. We here report a case of 14 year old male who initially presented with manic symptoms and then subsequently diagnosed to be suffering from SSPE. Improtance of ruling our organic conditions is emphasized.


Manic episode; periodic complex; subacute sclerosing panencephalitis

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