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Andrologia. 2012 May;44 Suppl 1:833-5. doi: 10.1111/j.1439-0272.2011.01208.x. Epub 2011 Aug 2.

Anejaculatory infertility due to multiple sclerosis.

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Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Miami Miller School of Medicine, Miami, FL, USA.


There are few reports of pregnancy outcomes in couples with anejaculatory infertility secondary to multiple sclerosis and no longitudinal reports of semen quality in this population. We report our experience with one such case. The couple achieved two live births from spermatozoa obtained with electroejaculation: the first by intrauterine insemination and the second by in vitro fertilisation with intracytoplasmic sperm injection of donor oocytes. Linear regression analysis showed no progressive decline in semen parameters across 26 semen retrievals performed over 7.7 years. Years of disease do not appear to cause progressive decline in semen quality.

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