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Urol Nurs. 2011 May-Jun;31(3):181-2, 194.

C-reactive protein may represent sensitive measure of renal cell carcinoma metastasis.

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Department of Urology, Emory University, Atlanta, GA, USA.


A patient with localized kidney cancer underwent potentially curative nephrectomy. Routinely post-operative serum C-Reactive Protein (CRP) values were measured. At 25 months post-operatively, lung imaging suggested possible metastasis. However, CRP levels remained at baseline. Subsequent resection revealed a benign mass. CRP values have been shown to carry prognostic significance for overall and disease free survival. This case suggests a novel use for CRP: a sensitive biomarker of disease recurrence and metastasis.

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