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Catheter Cardiovasc Interv. 2012 Apr 1;79(5):726-32. doi: 10.1002/ccd.23275. Epub 2011 Dec 12.

Incidence, timing, and predictors of valve dislodgment during TAVI with the Medtronic Corevalve System.

Author information

1
Department of Interventional Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands. n.vanmieghem@erasmusmc.nl

Abstract

OBJECTIVES:

To determine the incidence, timing and predictors of periprocedural valve dislodgment with the Medtronic Corevalve System (MCS).

BACKGROUND:

Periprocedural valve dislodgment may occur during transcatheter aortic valve implantation (TAVI).

METHODS:

Ninety-eight consecutive patients underwent TAVI with the MCS after a comprehensive baseline assessment including invasive angiography, echocardiography, and Multi-Slice Computed Tomography (MSCT). The invasive monitoring charts and angiographic studies of all TAVI procedures were reviewed to determine the incidence and timing of valve dislodgment.

RESULTS:

Valve dislodgment occurred in 18 patients. Patients with valve dislodgment had a larger Aortic Valve Area (0.76 ± 0.25 cm(2) vs. 0.61 ± 0.19 cm(2) , P = 0.007), lower mean transaortic gradient (37.65 ± 14.62 mm Hg vs. 47.11 ± 16.08 mm Hg, P = 0.03) and significantly less aortic root calcification (Agatston score median 1951 AU (IQR, 799-3103) vs. 3289 AU (IQR 2097-4481), P = 0.016). A lower aortic root calcium score (Agatston score < 2359 AU) was the single independent predictor for valve dislodgment (OR 3.10, 1.09-8.84). After valve dislodgment, the valve could be successfully retrieved and implanted in the proper anatomic location in all cases. Valve dislodgment was associated with a lower incidence of post-procedural AR ≥ 2 (11.1% vs. 34.6%, P = 0.05). There were no relevant procedural or clinical implications to valve dislodgment.

CONCLUSIONS:

The incidence of periprocedural valve dislodgment was 18% in these series. Less aortic root calcification appeared the single independent predictor.

PMID:
21805601
DOI:
10.1002/ccd.23275
[Indexed for MEDLINE]

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