Format

Send to

Choose Destination
See comment in PubMed Commons below
Cardiol Clin. 2011 Aug;29(3):447-59. doi: 10.1016/j.ccl.2011.06.004.

Ventricular-vascular interaction in heart failure.

Author information

1
Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA. borlaug.barry@mayo.edu

Abstract

Nearly half of all patients who have heart failure have preserved ejection fraction (HFpEF). Patients who have HFpEF tend to be older, female, and hypertensive, and characteristically display increased ventricular and arterial stiffening. In this article, we discuss the pathophysiology of abnormal ventriculoarterial stiffening and how it affects ventricular function, cardiovascular hemodynamics, reserve capacity, and symptoms. We conclude by exploring how novel treatment strategies targeting abnormal ventricular-arterial interaction might prove useful in the treatment of patients who have HFpEF.

Republished from

PMID:
21803232
DOI:
10.1016/j.ccl.2011.06.004
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center