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Arch Dis Child. 2012 Apr;97(4):372-5. doi: 10.1136/adc.2011.214205. Epub 2011 Jul 27.

Cardiovascular dysfunction in infants with neonatal encephalopathy.

Author information

1
Department of Paediatrics, National Maternity Hospital, Holles St, Dublin 2, Ireland. katey21@hotmail.com

Abstract

Severe perinatal asphyxia with hypoxic ischaemic encephalopathy occurs in approximately 1-2/1000 live births and is an important cause of cerebral palsy and associated neurological disabilities in children. Multiorgan dysfunction commonly occurs as part of the asphyxial episode, with cardiovascular dysfunction occurring in up to a third of infants. This narrative paper attempts to review the literature on the importance of early recognition of cardiac dysfunction using echocardiography and biomarkers such as troponin and brain type natriuretic peptide. These tools may allow accurate assessment of cardiac dysfunction and guide therapy to improve outcome.

PMID:
21798875
DOI:
10.1136/adc.2011.214205
[Indexed for MEDLINE]

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