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Expert Rev Neurother. 2011 Aug;11(8):1151-63. doi: 10.1586/ern.11.94.

Prolonged exposure therapy for post-traumatic stress disorder: a review of evidence and dissemination.

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Center for the Treatment and Study of Anxiety, University of Pennsylvania, 3535 Market Street, 6th Floor, Philadelphia, PA 19104, USA.


Post-traumatic stress disorder (PTSD) is a highly prevalent, often chronic and disabling psychiatric disorder that is associated with significant adverse health and life consequences. Fortunately, there is compelling evidence that cognitive-behavioral therapies, notably exposure therapies, are effective in reducing PTSD symptomology relative to waiting list and active control conditions. Prolonged exposure is a specific exposure therapy program that is considered a first-line evidence-based treatment for PTSD. Unfortunately, barriers to treatment dissemination prevent the majority of individuals with PTSD from receiving evidence-based treatment. Strategies to increase the availability of treatment and boost the efficiency of exposure therapy are now being examined.

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