Format

Send to

Choose Destination
Reumatol Clin. 2009 Nov-Dec;5(6):259-63. doi: 10.1016/j.reuma.2009.01.007. Epub 2009 Sep 26.

[Primary hypertrophic osteoarthropathy (pachydermoperiostosis). Report of two familial cases and literature review].

[Article in Spanish]

Author information

1
Servicio de Reumatología, Hospital POVISA, Vigo, Pontevedra, España.

Abstract

The primary hypertrophic osteoarthropathy (pachydermoperiostosis) is a hereditary disease characterized by skin thickening (pachydermia), finger clubbing, and proliferation of periosteum (periostitis) with subperiosteal new bone formation. We describe the cases of two brothers of 30 and 24 years, who consulted due to bone pain, arthralgia and oligoarthritis. Pachydermia, hyperhidrosis, seborrhea, digital clubbing, periostosis and non-inflammatory effusions of the knees. The first had been diagnosed with juvenile idiopathic arthritis at age 15, while the youngest also presented with a thoracic scoliosis, hypertrophic gastritis, iron deficiency anemia and glucose intolerance by pancreatic endocrine dysfunction. In both patients, symptoms were controlled satisfactorily with etoricoxib (90mg/day) and risedronate (35mg/week).

PMID:
21794626
DOI:
10.1016/j.reuma.2009.01.007
Free full text

Supplemental Content

Full text links

Icon for Ediciones Doyma, S.L.
Loading ...
Support Center