Format

Send to

Choose Destination
Curr Biol. 2011 Jul 26;21(14):R560-9. doi: 10.1016/j.cub.2011.06.019.

Building distinct actin filament networks in a common cytoplasm.

Author information

1
Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA. amichelot@berkeley.edu

Abstract

Eukaryotic cells generate a diversity of actin filament networks in a common cytoplasm to optimally perform functions such as cell motility, cell adhesion, endocytosis and cytokinesis. Each of these networks maintains precise mechanical and dynamic properties by autonomously controlling the composition of its interacting proteins and spatial organization of its actin filaments. In this review, we discuss the chemical and physical mechanisms that target distinct sets of actin-binding proteins to distinct actin filament populations after nucleation, resulting in the assembly of actin filament networks that are optimized for specific functions.

PMID:
21783039
PMCID:
PMC3384529
DOI:
10.1016/j.cub.2011.06.019
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center