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J Med Case Rep. 2011 Jul 22;5:322. doi: 10.1186/1752-1947-5-322.

Ganglioneuroblastoma of the posterior mediastinum: a case report.

Author information

1
Aga Khan University, Stadium Road, Karachi 74800, Pakistan. ashfaq.awais@gmail.com.

Abstract

INTRODUCTION:

Ganglioneuroblastoma is a rare peripheral neuroblastic tumor that is derived from developing neuronal cells of the sympathetic nervous system, and is found mostly, but not exclusively, in babies and young children.

CASE PRESENTATION:

To the best of our knowledge, there have been no previously reported cases of ganglioneuroblastoma of the mediastinum from Pakistan. We present a case of ganglioneuroblastoma in an eight-year-old Pakistani Sindhi boy incidentally found to have a large posterior mediastinal mass that on biopsy initially looked like ganglioneuroma. He underwent successful excision of the mediastinal mass and remained stable post-operatively. Final pathology findings showed a ganglioneuroblastoma. He has remained free of symptoms on long-term follow-up.

CONCLUSIONS:

The rarity of this tumor along with its almost exclusive occurrence in the pediatric population necessitates a thorough investigation of patients presenting with a symptomatic mass.

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