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J Biophotonics. 2011 Aug;4(7-8):509-13. doi: 10.1002/jbio.201000112. Epub 2010 Dec 13.

Dynamic microvascular responses with a high speed TiVi imaging system.

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Department of Medical Physics, Royal Surrey County Hospital, Egerton Road, Guildford GU27XX, UK. jim.o'


TiVi technology presents a high resolution, low speed methodology for imaging microcirculation. Recently, the TiVi system was adapted to produce a high speed system capable of analysing dynamic responses from human tissues at a frame rate of 30 frames per second. We present results based on this system by investigating dynamic responses such as arterial pulsations both from a controlled flow model and in vivo tissue sites. We also quantify the effects of sympathetic vasomotion, a biological effect which is evident in many tissue sites, and show that the effects of arterial pulsations and vasomotion on the resulting TiVi time traces are easily determined.

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