The emergence of supportive oncodermatology: the study of dermatologic adverse events to cancer therapies

J Am Acad Dermatol. 2011 Sep;65(3):624-635. doi: 10.1016/j.jaad.2010.06.051. Epub 2011 Jul 20.

Abstract

Cancer therapies have led to remarkable results due to improved toxicity profiles and effects on survival. While these medical, surgical, and radiation protocols are chiefly responsible for these noteworthy contributions, an unexpected constellation of toxicities has emerged. Most notably, dermatologic adverse events have gained considerable attention, due to their high frequency, visibility, and impact on physical and psychosocial health, all of which affect dose intensity and possibly clinical outcome. Consequently, increased attention to cutaneous health in oncology has resulted in supportive oncodermatology clinical programs and toxicity-driven investigations, aiming to mitigate these untoward events and permit the continued optimization of cancer treatments.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Epidermal Growth Factor / antagonists & inhibitors
  • Humans
  • Neoplasms / drug therapy
  • Neoplasms / radiotherapy
  • Neoplasms / surgery
  • Neoplasms, Radiation-Induced / etiology
  • Postoperative Complications
  • Radiodermatitis / etiology
  • Radiotherapy / adverse effects*
  • Skin Diseases / chemically induced*

Substances

  • Antineoplastic Agents
  • Epidermal Growth Factor