Send to

Choose Destination
See comment in PubMed Commons below
Am J Clin Nutr. 2011 Sep;94(3):877-83. doi: 10.3945/ajcn.111.015776. Epub 2011 Jul 20.

Association of body fat percentage with lipid concentrations in children and adolescents: United States, 1999-2004.

Author information

Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD, USA.



BMI is one factor that is used to determine a child's eligibility for lipid screening and treatment. BMI, which is an indirect measure of body fat, may inadequately represent the biological effect of body fat percentage on lipid concentrations.


We examined the relation between directly measured body fat percentage and lipid concentrations in a representative sample of US youths.


Data from 7821 participants aged 8-19 y from the 1999-2004 NHANES were analyzed. Body fat percentage was measured by dual-energy X-ray absorptiometry. Total and HDL-cholesterol concentrations were measured in serum. Serum triglyceride and LDL-cholesterol concentrations were measured in a subsample of 2661 fasting NHANES participants aged 12-19 y. Prevalences of adverse total cholesterol (>200 mg/dL), LDL cholesterol (>130 mg/dL), triglycerides (>150 mg/dL), and HDL cholesterol (<35 mg/dL) were measured.


Approximately 10.0% [±0.7% (SE)] of participants had high total cholesterol, 7.0 ± 0.4% of participants had low HDL cholesterol, 9.7 ± 1.0% of participants had high triglycerides, and 7.6 ± 0.7% of participants had high LDL cholesterol. Prevalence of adverse total cholesterol, HDL cholesterol, triglycerides, and LDL cholesterol in US youths with high adiposity (greater than or equal to the age- and sex-specific 75th percentile of body fat percentage) was significantly greater (P < 0.01) than for participants without high adiposity. In multiple linear regressions adjusted for age, survey period, and race-ethnicity, the variance in lipid concentrations explained by body fat percentage was 2-20% (P < 0.001).


Adverse lipid concentrations and high adiposity are significantly associated in youths.

[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center