Format

Send to

Choose Destination
See comment in PubMed Commons below
Front Pharmacol. 2011 Jun 30;2:33. doi: 10.3389/fphar.2011.00033. eCollection 2011.

In silico toxicology - non-testing methods.

Author information

1
Faculty of Health Sciences, University of Eastern Finland Kuopio, Finland.

Abstract

In silico toxicology in its broadest sense means "anything that we can do with a computer in toxicology." Many different types of in silico methods have been developed to characterize and predict toxic outcomes in humans and environment. The term non-testing methods denote grouping approaches, structure-activity relationship, and expert systems. These methods are already used for regulatory purposes and it is anticipated that their role will be much more prominent in the near future. This Perspective will delineate the basic principles of non-testing methods and evaluate their role in current and future risk assessment of chemical compounds.

KEYWORDS:

REACH; in silico; modeling; toxicity

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Frontiers Media SA Icon for PubMed Central
    Loading ...
    Support Center