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Curr Opin Rheumatol. 2011 Sep;23(5):484-91. doi: 10.1097/BOR.0b013e328349c2d2.

Imaging of osteoarthritis: update from a radiological perspective.

Author information

1
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA. guermazi@bu.edu

Abstract

PURPOSE OF REVIEW:

Imaging plays an increasingly important role in the continuing effort to understand the pathogenesis of osteoarthritis and in the quest for disease-modifying osteoarthritis drugs. To assist investigators in choosing the appropriate imaging technique for a particular goal of a study, this review describes, from a radiological point of view, key studies that were published between May 2010 and May 2011.

RECENT FINDINGS:

MRI and ultrasound are the two key modalities for osteoarthritis research today. MRI offers semiquantitative, quantitative and compositional assessment. The importance of contrast-enhanced MRI for synovitis assessment has been demonstrated by several studies. Radiography still has a role in clinical trials in light of regulatory requirements, but investigators need to be aware of its inherent limitations. MRI is the best modality for imaging of osteoarthritis: its strengths and unique advantages include ability to visualize multiple individual tissue pathologies relating to pain and also to predict clinical outcome.

SUMMARY:

MRI enables multitissue morphologic and compositional assessment of the joint. Contrast-enhanced MRI is essential for evaluation of synovitis in knee osteoarthritis. Ultrasound is a useful technique for assessing synovitis and structural damage especially in hand osteoarthritis.

PMID:
21760511
DOI:
10.1097/BOR.0b013e328349c2d2
[Indexed for MEDLINE]

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