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Trends Plant Sci. 2011 Oct;16(10):558-67. doi: 10.1016/j.tplants.2011.06.003. Epub 2011 Jul 13.

Plant protein-coding gene families: emerging bioinformatics approaches.

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1
Centro de Biotecnología y Genómica de Plantas (UPM-INIA), Campus Montegancedo, Universidad Politécnica de Madrid. Autovía M40 (Km 38), 28223-Pozuelo de Alarcón, Madrid, Spain. m.martinez@upm.es

Abstract

Protein-coding gene families are sets of similar genes with a shared evolutionary origin and, generally, with similar biological functions. In plants, the size and role of gene families has been only partially addressed. However, suitable bioinformatics tools are being developed to cluster the enormous number of sequences currently available in databases. Specifically, comparative genomic databases promise to become powerful tools for gene family annotation in plant clades. In this review, I evaluate the data retrieved from various gene family databases, the ease with which they can be extracted and how useful the extracted information is.

PMID:
21757395
DOI:
10.1016/j.tplants.2011.06.003
[Indexed for MEDLINE]
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