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Kaohsiung J Med Sci. 2011 Jul;27(7):289-91. doi: 10.1016/j.kjms.2010.08.005. Epub 2011 Apr 17.

Nasopharyngeal carcinoma with pericardial metastasis.

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1
Division of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, Taiwan.

Abstract

Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein-Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.

PMID:
21757147
DOI:
10.1016/j.kjms.2010.08.005
[Indexed for MEDLINE]
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