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Acta Orthop. 2011 Aug;82(4):423-6. doi: 10.3109/17453674.2011.596063. Epub 2011 Jul 13.

High-volume infiltration analgesia in bilateral hip arthroplasty. A randomized, double-blind placebo-controlled trial.

Author information

1
Department of Anesthesiology, Hvidovre Hospital, Copenhagen, Denmark lasseandersen@email.dk

Abstract

BACKGROUND AND PURPOSE:

High-volume infiltration analgesia may be effective in postoperative pain management after hip arthroplasty but methodological problems prevent exact interpretation of previous studies.

METHODS:

In a randomized, double-blind placebo-controlled trial in 12 patients undergoing bilateral total hip arthroplasty (THA) in a fast-track setting, saline or high-volume (170 mL) ropivacaine (0.2%) with epinephrine (1:100,000) was administered to the wound intraoperatively along with supplementary postoperative injections via an intraarticular epidural catheter. Oral analgesia was instituted preoperatively with a multimodal regimen (gabapentin, celecoxib, and acetaminophen). Pain was assessed repeatedly for 48 hours postoperatively, at rest and with 45° hip flexion.

RESULTS:

Pain scores were low and similar between ropivacaine and saline administration. Median hospital stay was 4 (range 2-7) days. Interpretation Intraoperative high-volume infiltration with 0.2% ropivacaine with repeated intraarticular injections postoperatively may not give a clinically relevant analgesic effect in THA when combined with a multimodal oral analgesic regimen with gabapentin, celecoxib, and acetaminophen.

PMID:
21751861
PMCID:
PMC3237031
DOI:
10.3109/17453674.2011.596063
[Indexed for MEDLINE]
Free PMC Article
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