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Chem Commun (Camb). 2011 Aug 21;47(31):8925-7. doi: 10.1039/c1cc11726b. Epub 2011 Jul 11.

A facile, modular and high yield method to assemble three-dimensional DNA structures.

Author information

1
Department of Chemistry, 801 Sherbrooke St. West, Montreal, QC, Canada H3A 2K6.

Abstract

We describe a rapid and quantitative method to generate DNA cages of deliberately designed geometry from readily available starting strands. Balancing the incorporation of sequence uniqueness and symmetry in a face-centered approach to 3D construction can result in triangular (TP), rectangular (RP), and pentagonal prisms (PP) without compromising the potential for nanostructure addressability.

PMID:
21748162
DOI:
10.1039/c1cc11726b
[Indexed for MEDLINE]

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