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Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 Jul-Aug;40(4):762-6.

[The modulation of postural asymmetry in recipient animals under the influence of the cerebrospinal fluid from patients with manic-depressive psychosis].

[Article in Russian]


Suboccipital administration of cerebrospinal fluid of patients with affective disorders elicits a pose asymmetry in rats-recipients; the character of the pose asymmetry depends on the phase of donor's disease: cerebrospinal fluid of manic patients elicits a relative flexion of the right posterior limb, of depressive patients--a relative flexion of the left posterior limb. High-molecular and low-molecular fractions of the cerebrospinal fluid were active, trypsin treatment led to disappearance of the effect. The results suggest a significant role of protein components of the cerebrospinal fluid in the organization of the symptom of functional asymmetry of the central nervous system under affective disorders.

[Indexed for MEDLINE]

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