Format

Send to

Choose Destination
See comment in PubMed Commons below
J Infect Dis. 2011 Aug 1;204(3):372-6. doi: 10.1093/infdis/jir285.

Incremental impact of adding boys to current human papillomavirus vaccination programs: role of herd immunity.

Author information

1
Unité de Recherche en Santé des Populations, Centre de Recherche Fonds de la Recherche en Santé du Québec du Centre Hospitalier affilié Universitaire de Québec, Canada. marc.brisson@uresp.ulaval.ca

Abstract

Our aim was to examine the potential incremental impact of vaccinating boys against human papillomavirus (HPV) on vaccine-type infection in females and males, using an individual-based HPV transmission-dynamic model. Under base assumptions (vaccine efficacy = 99%, duration of protection = 20 years, coverage = 70%), vaccinating 12-year-old boys, in addition to girls, resulted in an incremental reduction in HPV-16/18 (HPV-6/11) incidence over 70 years of 16% (3%) in females and 23% (4%) in males. The benefit of vaccinating boys decreased with improved vaccination coverage in girls. Given the important predicted herd immunity impact of vaccinating girls under moderate to high vaccine coverage, the potential incremental gains of vaccinating boys are limited.

PMID:
21742835
DOI:
10.1093/infdis/jir285
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Support Center