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Br J Pharmacol. 2012 Apr;165(7):2015-33. doi: 10.1111/j.1476-5381.2011.01588.x.

Use of inotropes and vasopressor agents in critically ill patients.

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1
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, UK.

Abstract

Inotropes and vasopressors are biologically and clinically important compounds that originate from different pharmacological groups and act at some of the most fundamental receptor and signal transduction systems in the body. More than 20 such agents are in common clinical use, yet few reviews of their pharmacology exist outside of physiology and pharmacology textbooks. Despite widespread use in critically ill patients, understanding of the clinical effects of these drugs in pathological states is poor. The purpose of this article is to describe the pharmacology and clinical applications of inotropic and vasopressor agents in critically ill patients.

PMID:
21740415
PMCID:
PMC3413841
DOI:
10.1111/j.1476-5381.2011.01588.x
[Indexed for MEDLINE]
Free PMC Article
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