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Indian J Clin Biochem. 2010 Jul;25(3):295-301. doi: 10.1007/s12291-010-0044-8. Epub 2010 Aug 25.

A community based study of the relationship between homocysteine and some of the life style factors.

Author information

  • 1Biochemistry Lab, Department of Pathology and Microbiology, GNRC Hospitals, Dispur, Guwahati, 781006 Assam India.

Abstract

Till date no community based data on plasma homocysteine is available in North Eastern Region. Hence, the present study was conducted to analyze and correlate the plasma homocysteine level with some life style factors like diet, alcohol intake, smoking habit and body weight, in a cross-section of population. 12 h fasting samples of 970 apparently healthy, Assamese population of both genders in the age group of 35-86 years, mostly from the urban area of Assam were tested for plasma total homocysteine level over a period of 3 years. Out of 970 volunteers, hyperhomocysteinemia was detected in 533 (55%) individuals with a mean value of 18.41 μmol/l. Of that hyperhomocysteinemia, 89.1% were in the range of moderately high and rest 10.9% were intermediate high. Another finding was that males had a tendency towards greater value (mean = 20.36 μmol/l) than females (mean = 16.37 μmol/l). It was observed that the relationship of homocysteine levels to gender and some of the life style factors were also significant.

KEYWORDS:

Age; Alcohol; Dietary habit; Gender; Homocysteinemia; Life style; Obesity; Smoking

PMID:
21731201
PMCID:
PMC3001846
DOI:
10.1007/s12291-010-0044-8
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