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Cell Metab. 2011 Jul 6;14(1):3-4. doi: 10.1016/j.cmet.2011.06.006.

Inflaming hypothalamic neurons raises blood pressure.

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Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.


Obesity and hypertension are strongly associated, and neural dysfunction has been implicated in both. The hypothalamus integrates signals regulating blood pressure and energy homeostasis. A recent paper in Nature Medicine (Purkayastha et al., 2011) suggests that obesity and hypertension are caused by inflammation in distinct hypothalamic neuronal populations.

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