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Biocontrol Sci. 2011 Jun;16(2):69-72.

Roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12.

Author information

1
Department of Food Bioscience and Biotechnology, College of Bioresource Science, Nihon University, Kameino, Fujisawa, Japan. furukawa@brs.nihon-u.ac.jp

Abstract

We genetically analyzed the roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12 BW25113. We used 22 mutants missing various genes related to the multidrug efflux pumps and found that the biofilm formation of emrD, emrE, emrK, acrD, acre and mdtE-deleted mutants was extremely decreased. These results indicate that some multidrug efflux pumps significantly contribute to the biofilm formation of E. coli.

PMID:
21719992
[Indexed for MEDLINE]
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